RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-24-1
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
PCR; Masson's trichrome staining
Target
FURIN
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
"Role of miR-24, Furin, and Transforming Growth Factor-b1 Signal Pathway in Fibrosis After Cardiac Infarction"
Year
2017
Function
miR-24 exerted its function via targeting furin and hence inhibiting TGF-beta1 activation. The present study thus investigated the role of miR-24 and furin/TGF-beta1 in rat myocardial fibrosis.